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demonstrated that VC kills drug-susceptible and drug-resistant Mtb via Fenton reaction in a dose-dependent manner in vitro , and 4 mM of VC completely sterilized Mtb culture at three weeks after treatment (187)

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Knockdown of endogenous GPX4 or blockade of GPX4 using a specific inhibitor enhanced the chemosensitivity of EBV-infected NPC cells

Elevated ATF3 expression in aging osteocytes promotes iron uptake by upregulating TFR1 while inhibiting SLC7A11-mediated cystine uptake, leading to iron overload and lipid peroxidation, ultimately resulting in ferroptosis