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Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes

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A case report published in Cureus described a biphasic anaphylactic reaction occurring 20 minutes after tirzepatide injection, with diffuse urticaria, throat swelling, shortness of breath, and wheezing

Physical symptoms can compound the picture: palpitations and shortness of breath from anemia sometimes feel indistinguishable from panic attacks

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