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Because of their exceptional biological activities, these compounds have gained the attention of researchers in various fields, including those investigating natural product-derived medicines as well as chemists, biochemists, and microbiologists

Animal studies have shown that FUS can improve the penetration of immunotherapy into brain tumors, the immune response against the cancer cells, and survival outcomes (139, 140)

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Thus, pyruvate restores the redox potential of GSH, the major antioxidant by providing NADPH reducing equivalents

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