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Misfolded wild type SOD1 is observed in sALS cases and the existing treatments for SOD1-related fALS, such as the antisense oligonucleotide therapy Tofersen, may have a possibility to be applied to these sALS cases (Marlow et al., 2025)

to Leiden University for their support of metabolomics and statistical analyses

[Google Scholar] Prion-like propagation of protein misfolding and aggregation in amyotrophic lateral sclerosis

Allergy 74 , 23202328 (2019)

Two to Four Weeks: With consistent treatments, patients typically experience more substantial benefits including improved immune response, enhanced energy reserves, and often noticeable improvements in skin clarity and tone

In addition, if lycopene and alpha-tocopherol have similar antioxidant functions (fat-soluble antioxidants), lycopenes potential antioxidant action is redundant to alpha-tocopherols antioxidant function and thus, also less likely to be a meaningful antioxidant