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doi: 10.3389/fphys.2015.00363 Received 02 September 2015 Accepted 16 November 2015 Published 26 January 2016 Volume 6 - 2015 Edited by Honglei Weng, University of Heidelberg, Germany Reviewed by Sandeep Kumar, State University of New York College of Optometry, USA

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H 2 S 2 and H 2 S 3 as well as H 2 S were produced in the presence of 3MP in lysates of COS cells expressing 3MST as previously reported (Supplementary Figs S2 and S4ac) 14

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The entourage effect gained prominence during this period, underscoring the synergistic interactions among cannabinoids, terpenes, and other phytochemicals in hemp [17]