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However, as the development of multi-specific protein therapeutics becomes more widespread, the potential for immune complex formation and consequent immunogenicity must be considered, as the latter can lead to both loss of pharmacodynamic activity and safety concerns

Kassar-Duchossoy L, et al

My legs did become weak yes & walking down any steps or stairs they would constantly shake, this started around 3 years ago, along with bumping into door frames & losing my balance etc

However, the precise mechanism by which NMT1 integrates into the dynamic environment of the translating ribosome, and how its co-translational activity is coordinated with that of both human MetAPs and other ribosome-associated enzymes remain unclear

46 MissallT

Genetic analysis reveals AMPK is required to support Tumor Growth in Murine Kras-Dependent Lung Cancer models