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A vial that moves from freezer to room temperature and back again over and over may collect condensation risk and experience more stress than a vial that stays in one stable cold environment

BioMed Research International, 2014

For instance, the release of Smac/Diablo into the cytosol ensures the efficiency of caspase 3 in proteolyzing target proteins through inhibition of inhibitor of apoptosis proteins (IAPs)

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But and this is the part NO ONE wants to hear peptides are the last step, not the first