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Chemotherapeutic drugs such as methotrexate, 5-fluorouracil, 8-azaguanine, and cisplatin are most affected by this resistance mechanism

Because of the diets dramatic limitation of caloric intake, theres no room for the nine calories per gram of fats

Ethacraplatin is also able to revert cisplatin resistance in microsomal GST1-1 overexpressing cells 94

In the process of metabolizing neurotransmitters, monoamine oxidase B enzyme uses FAD (derived from riboflavin ) and produces hydrogen peroxide .[ref] Excess hydrogen peroxide causes oxidative stress, so MAO-B needs to be maintained at the right levels

Zhang C, Lu X, Liu X, Xu J, Li J, Qu T, et al

Traynelis SF, et al