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Peptides with fewer residues are more susceptible to rapid enzymatic degradation, leading to shorter systemic exposure. Fosgerau & Hoffmann, Drug Discovery Today Half-Life Each peptide has a defined biological half-life the time it takes for half of the substance to be eliminated from the bloodstream

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FSP1 functions as an alternative pathway to GPX4, protecting cells from ferroptosis

Mitochondrial iron metabolism in cancer Mitochondria serve as the central hub for iron utilization in cancer cells, directly linking iron metabolism to tumor bioenergetics, redox balance, and therapeutic resistance