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Di Cesare Mannelli et al., 2014)

Furthermore, as expected, our data indicate the existence of a trade-off between glutathione biosynthetic activity and cellular viability and fitness beyond a certain threshold, suggesting that an optimum should be aimed for in a possible strain engineering strategy

As such, in 2014, the TGA undertook a complete de novo evaluation of NCEs, regardless of approval status by another NRA, resulting in duplication of regulatory efforts and processes

Biochimica biophysica acta 1813 (5), 10031013

Three concentrations (2500, 5000 and 10,000 cells) were used for Telomeric Repeat Amplification Protocol (TRAP) reactions to ensure that the assay for each sample is in the linear range

Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells