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However, many people struggle to absorb enough due to gastrointestinal conditions, age, or lifestyle factors such as vegan and vegetarian diets

The current study provides conclusive evidence for the use of small molecule, drug-like NNMT inhibitors as a viable therapeutic approach to manage diet-induced obesity and related metabolic comorbidities

Methylation and methyl donor status NNMT consumes methyl donors as part of its enzymatic function

Its value in a clinical setting comes from what it is not: it does not disrupt appetite, hormones, insulin, or IGF-1

Injections may be preferred when absorption is poor, symptoms are significant, or a clinician wants a more direct replacement route

However, for long-term storage, it is recommended to store them in the freezer