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SKU: 44566469131
Price: 20.08 USD
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Rating: 4.710100000000001 (24 reviews)

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Description

The intestinal barrier consists of several layers, with the outermost layer consisting of the mucus layer, commensal gut microbiome, and defense proteins, followed by intestinal epithelial cells (IECs) in the middle layer, and the innermost layer comprising immune cells [106]

In IPF, this protective mechanism is compromised

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[DOI] [PubMed] [Google Scholar] 73.Okey A.B

At this stage, macrophages in a pro-fibrotic state (functionally analogous to the traditional M2a subtype) form a fatal alliance with fibroblasts, becoming the direct executors of fibrosis