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Echocardiography was performed before, directly after and 5 h after intracardiac injection of B-017 (0.8 mg kg 1 BW in 50 l 0.9% NaCl) using a Vevo 2100 Imaging System (FUJIFILM VisualSonics, Inc.)

Cell Death Differ (2016) 23(3):36979

Nitric oxide is synthesized by nitric oxide synthases (NOS) and plays vital roles in vascular regulation, neurotransmission, and immune responses [5, 30]

IHC revealed decreased -synuclein protein levels, indicating reduced neuronal damage, and increased brain-derived neurotrophic factor (BDNF) levels, confirming neuroprotection

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This article provides the first comprehensive account of six aspects of the medicinal history, species, chemical composition, pharmacological activity, toxicology, and clinical application of coral in China