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doi: 10.1016/j.celrep.2021.109344 37 LacailleVKapinskyM

It is commonly studied in preclinical models involving satiety hormones, feeding behavior, and energy regulation systems

HM12525A) is also a unimolecular once weekly GLP-1 and glucagon agonist that has been investigated in people with obesity, T2D and MASLD/MASH

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This is especially beneficial for individuals whose bodies struggle to absorb B12 from food or oral supplements due to conditions like pernicious anaemia, where the immune system attacks cells in the stomach that help absorb B12

Many studies are small, variably designed, or lack long-term follow-up