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Surprisingly, these animals do not show multiorgan autoimmunity, but develop an AIH-1 like disease, with interface hepatitis, positive ANA and anti-SLA antibodies, suggesting that intact central tolerance is key to prevent AIH-1 [118]

Su Y, Zhao B, Zhou L, Zhang Z, Shen Y, Lv H, et al

Nonalcoholic fatty liver disease and hypercholesterolemia: roles of thyroid hormones, metabolites, and agonists

Notably, TCMs historical use of Jin Zhi (golden juice, a fecal-based medicine) represents an early precursor to modern microbiota transplantation (Shi and Yang, 2017