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(2016) 14:160211.e5

The effect of the decrease in serum levels of dehydroepiandrosterone (DHEA) and hirsutism occurs by improving insulin metabolism markers

Formation of atheroma Endothelial cells secret small peptides such as cytokines and growth factors like interleukin 1 (IL-1) and TNF causing smooth muscle cell migration and synthesized extracellular matrix

Lima et al., 2010)

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These insights underscore the need for combinatorial therapies that integrate epigenetic modulation, pathway inhibition, and apoptotic sensitization to overcome adaptive resistance (Tables 3 and 4) [160]