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At resting membrane potential, the NMDA receptor channel is blocked by Mg 2+ that is released upon depolarization, allowing cation transport across the pore

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The Funnel plot was significantly asymmetrical denoting the presence of publication bias (p=0.02) (Fig

There is also an endogenous predisposition that relates to the malfunctioning of epidermal proteins such as filaggrin, ceramides, claudins, antimicrobial factors, and proteases [110]