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Methods This narrative review synthesizes perspectives from both bioactive and engineered peptide classes across musculoskeletal medicine

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This includes the following patient groups: - Those who follow a strictly vegan diet - Those over the age of 50 - Those who take certain medications that are known to inhibit the absorption of B12 - Those who have an autoimmune disorder - Those who have gastrointestinal disorders - Those who have issues with stomach ulcers, atrophic gastritis, and other similar health problems SYMPTOMS OF A B12 DEFICIENCY Whether you fall into any of the categories above or not, there are certain signs to be aware of that could mean that you are suffering from a vitamin B12 deficiency

The 2024 NICE guideline on B12 deficiency in over-16s is built around identifying and treating the cause, not just topping up the number

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These often develop gradually and can go unnoticed for a long time, making early detection important