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This is supported by the finding that aging leads to more oxidation of the GSH and more damaged mtDNA in the mitochondria, which can be prevented by oral antioxidant administration

Statistical analysis GraphPad Prism (version 8.0.2) was used for all statistical analyses

Immunofluorescence analysis also revealed an enrichment of Fe2 in muscle satellite cells in the muscle tissue of the oe-TXNIP group (Fig

The R459 gating interaction with E220 appears to stabilise a bent conformation of TM11 (housing the critical carnitine-binding R471)

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TC is generally found in the serum added to the medium (although the protein composition of serum is not standardized)