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Gut 57 , 16981703 (2008)

Netherlands J Med 2007;65(11):411--18

Langer, G

Data resources used in this study are: hg38 genome FASTA ( CHIKV genome FASTA & annotation ( and DENV-2 genome (strain 16681) FASTA & annotation ( Site-directed mutagenesis (SDM) A single point mutation to mutate the DENV-2 motif 8 AAACA (92919295) into AAATA in the DENV-2 wild type plasmid (pFK-DVs) was generated using QuickChange XL site-directed mutagenesis kit (Agilent, 200517) according to the manufacturers instructions

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My research focus in RCC is in the following areas: Clinical and molecular characterization of non-clear cell RCC subtypes, particularly translocation RCC and renal medullary carcinoma Design and conduct of informative, biology-driven clinical trials for clear-cell and non-clear cell RCC Identification of circulating and tissue-based biomarkers of response to targeted agents and immune checkpoint antibodies in patients with clear-cell and non-clear cell RCC The projects outlined above are currently being carried out in the context of several investigator-initiated, approved, and funded clinical and laboratory trials in metastatic clear-cell and non-clear cell RCC, on which I serve as principal investigator