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Unlike the free form of GW2580, which has a short half-life in vivo, the synthesized NPs demonstrated prolonged retention at the lesion site

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doi:10.1016/j.abb.2005.06.023

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14 The sulfhydryl group interacts with different biochemical systems, therefore, the active form of glutathione is called GSH

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USP22 Protects Against Myocardial Ischemia-Reperfusion Injury via the SIRT1-p53/SLC7A11-Dependent Inhibition of Ferroptosis-Induced Cardiomyocyte Death[J]

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