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A summary of suggested mechanisms of action of environmental chemicals on DNA methylation machinery is shown in Figure 1

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In condizioni di iperglicemia e glicogeno elevato, aumenta il malonil-CoA , che inibisce CPT1 e riduce l'ingresso degli acidi grassi nei mitocondri (favorendo la sintesi lipidica)

These interactions underline the complexity of CD44s functions responsible for cancer progression and resistance to treatment

10.1073/pnas.1821332116 Proc Natl Acad Sci USA