Quantitative-Analysis of Amino-Acid Oxidation and Related Gluconeogenesis in Humans
As the completed molecule, GSH serves directly as a substrate and cofactor for multiple glutathione-dependent enzyme systems, making it a valuable research tool for investigating redox chemistry, thiol-disulfide exchange processes, enzyme-cofactor interactions, and glutathione-associated regulatory mechanisms
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doi: 10.1016/j.gene.2019.143956 115 LimDYJeongYTynerALParkJHY
This approach ensures that solubility measurements are both relevant and representative of real-world screening environments, supporting efficient decision-making in lead optimization
Acta 1819 , 921929 (2012)