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In this context, it has been shown that CAR-T cell therapy was an effective therapeutic strategy in in relapsed/refractory (R/R) B-ALL patients with Minimal residual disease (MRD) to induce MRD-negative complete remission (CR) before allo-HSCT [137, 138]

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Beyond doses of 200500 mg, absorption efficiency falls sharply, and higher oral doses commonly cause gastrointestinal discomfort, a particular concern for elderly patients

Mucin secretion is modulated by luminal factors in the isolated vascularly perfused rat colon

Assi, R, Benton CB, Al Rawi A, Chamoun K, Wang F, Pierce S, Patel KP, Hamilton BK, DiNardo CD, Garcia-Manero G, Kantarjian HM, Kadia T

CeO 2 NPs (60 mg/kg, i.p., daily for 4 weeks) offer protection against PIPN in rats since they significantly increased myelin protein zero (MPZ) expression, decreased the MDA levels, and reversed the histopathological changes in sciatic nerves and lumbar spinal cord caused by OXA