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Thereafter, the samples were centrifuged at 14,000 g for 10 min

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Single Oocyte/Embryo RNA Sequencing and Data Analysis For RNA sequencing (RNA-seq), the following samples were collected: 1) seven GV oocytes from patient 1 and ten GV oocytes from a control patient, from whom several embryos were collected for transfer during assisted reproductive technology, and 2) three 1-cell stage arrested embryos each from patient 1 and patient 2, and seven control 1-cell embryos of which previously described ( Result Clinical Characteristics of Patients Patient 1 from a consanguineous family, was 29 years old and diagnosed with primary infertility for unexplained reasons at 25 years of age

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The innate repair receptor (IRR) is a heterodimer of the EPO receptor and beta common receptor (CD131)

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Finally, the use of the Generalized Linear Mixed Model (GLMM) in our study allowed for a more comprehensive data analysis, considering additional covariates and their potential interactions throughout the treatment

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