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A chest examination completed by the GP was clear and non-remarkable

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Laron Z, Lilos P, Klinger B

Because hyperuricemia is a risk factor for gout, which usually manifests itself as an intense episode of pain in the metatarsophalangeal joint of the big toe, caused by the deposition of uric acid crystals and accompanied by swelling, possible redness, and inflammation

doi: 10.1089/ars.2015.6607

Circulation 124:17651773 Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M et al (2008) Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography