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More recently, using Magnetic Resonance Spectroscopy Imaging, it was demonstrated that hyperpolarized 13 C-labeled DHA is rapidly taken up by cancer cells and converted to vitamin C, illustrating the tumors' reducing state 4

4-20% SDS-PAGE gel

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While these shifts in the GSH/GSSG balance are essential for redox signaling and the maintenance of cellular metabolism and homeostatic function, sustained disequilibrium from excess GSSG formation ultimately increases protein mixed disulfide formation

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