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In hepatocytes, oxalate overload caused mitochondrial dysfunction and lipid accumulation by inhibiting the transcription of peroxisome proliferator-activated receptor and blocking mitochondrial FAO

Diamond-Blackfan Anemia Diamond-Blackfan anemia (DBA) is a genetically heterogeneous disorder usually transmitted as an autosomal dominant trait (8, 9, 10, 11, 12, 13)

Updated August 9, 2022

Pretorius E, Swanepoel AC, Buys AV, Vermeulen N, Duim W, Kell DB

SIRT3/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress

Studies also suggest that it may eventually be developed into an orally available and safe therapeutic agent for obesity, making it a convenient option for patients [2]