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Inhibiting COX-2 attenuated the rise of COX-2 levels and epithelial-mesenchymal transition (EMT) scores in NPC cells driven by MDSCs, suggesting COX-2 as a critical checkpoint for MDSCtumor cell interactions and tumor promotion [47]

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An increase in lipid peroxidation could affect the properties of the membrane and cellular homeostasis leading to apoptosis (Yadav et al., 2019)

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