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Matthew Kirkpatrick at the University of Chicago have linked to the drugs characteristic prosocial and empathogenic effects

reported that anoctamin 1 (ANO1) interacts with JUN to suppress CYP27A1-LXR signaling, leading to intracellular cholesterol accumulation and TME reprogramming, thus enhancing esophageal squamous cell carcinoma metastasis [79]

HMGB1 enhances the AGE-induced expression of CTGF and TGF-beta via RAGE-dependent signaling in renal tubular epithelial cells

Gu J, Chen C, Wang J, Chen T, Yao W, Yan T, Liu Z

The gut microbiota reduces leptin sensitivity and the expression of the obesity-suppressing neuropeptides proglucagon (Gcg) and brain-derived neurotrophic factor (Bdnf) in the central nervous system