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DAngelo S, Ingrosso D, Migliardi V, Sorrentino A, Donnarumma G, Baroni A, et al

Concurrently, the E3 ligase ZNRF2 tunes the ubiquitination of the auxiliary subunit SLC3A2 at K147, driving its plasma membrane translocation to maximize cystine import in lung adenocarcinoma, which can be therapeutically blocked by the synthetic peptide K147 [36]