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E.MerkA.ShaoJ.DaggupatiG.SrinivasanP.et al (2021)

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As a key transcription factor, NRF2 regulates antioxidant and detoxifying enzymes, bolstering the cells ability to resist oxidative stress, toxins, and other harmful stimuli, which can improve disease progression and prognosis [154, 155]

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Fish OilIncludes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure

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Metabolic activity assays in intact RBCs Washed RBCs were prepared in isotonic HEPES buffer containing either (i) 5 mM [U 13 C]-glucose (Isotec), (ii) 5 mM glucose, 5 mM alanine, and 5 mM [ 13 C 1,2,3,4 ]--ketoglutarate (Cambridge Isotope Laboratories) or (iii) 5 mM glucose and 1 mM [U 13 C 15 N] glutamine

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extracted BMSC-Exo using the magnetic bead affinity technique and examined its biological makeup

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