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All systems were energy-minimized and subsequently subjected to a 27 ns MD simulation for equilibration with decreasing positional restraints on protein coordinates

Jain N, Keating MJ, Thompson PA, Ferrajoli A, Burger JA, Borthakur G , Takahashi K, Estrov ZE, Fowler NH, Kadia TM, Konopleva MY, Alvarado Y, Yilmaz M, DiNardo CD, Bose P, Ohanian M, Pemmaraju N, Jabbour EJ, Sasaki K, Kanagal-Shamanna R, Patel K, Jorgensen JL, Garg N, Wang X, Sondermann K, Cruz N, Wei C, Ayala A, Plunkett W, Kantarjian H, Gandhi V, Wierda WG

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Its been shown that low levels of iron can compromise cognitive development, attention and memory resulting in difficulty concentrating

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Tox Appl Pharmacol