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The on-bench and in vitro experimental studies demonstrate that the characteristic hypercarbon-tetragold(I) multi-center bonding in PAA4 and PAA5 not only guarantees their stability under common physiological conditions, but also facilitates a glutathione (GSH)-triggered prompt and synergetic release of active Au(I) ions in the GSH-overexpressed and acidic microenvironment of human bladder cancer EJ cells

Excessive lipid peroxidation causes cell death in a unique pattern called ferroptosis

In the cyclic KD (CKD), periods of the KD and the high-carbohydrate diet are alternated [12]

Research suggests that it works by stimulating lipolysis (fat breakdown) and inhibiting lipogenesis (fat accumulation), particularly in stubborn fat deposits such as the abdomen and thighs

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doi: 10.1002/jbt.23307 277 TangCLiuJYangCMaJChenXLiuDet al