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Skeletal muscle protein balance regulation Skeletal muscle mass depends on the rates of protein synthesis and degradation

In: Litwack G (ed) Human biochemistry

Remarkably, GSH depletion significantly decreased the expression of these key fibrogenic factors under both chow and HFD conditions (Figure 3, A and B)

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Given the predicted reductase activity of Rha1 and Rha2 and their structural similarity to proteins that metabolize enone-containing compounds, we further investigated their role in 4-HNE resistance