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However, it is important to recognize that NLRP3 activation and IL-1 production are not essential for the immunity-promoting action of aluminum-based vaccine adjuvants but can be considered to be a source of inflammation-related reactogenicity [40, 41]

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Additionally, glycine synthesises crucial biomolecules, such as collagen and creatine, which contribute to tissue health and energy metabolism

10.1021/acschembio.2c00914 568 ZhuH.HuangJ.ChenY.LiX.WenJ.TianM.et al (2022)

The effect of prophylactic antipyretic administration on post-vaccination adverse reactions and antibody response in children: a systematic review