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Clinical cohort analyses report that hypermethylation of the OXTR (Oxytocin Receptor) gene in peripheral blood of ASD children inversely correlated with maternal Prevotella abundance ( Lactobacillus reuteri may induce hypomethylation at the Foxp3 locus, a key transcription factor for regulatory T cells, potentially via secretion of bioactive folate forms like 5-methyltetrahydrofolate, thereby mitigating neuroinflammation risk

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