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5-Amino-1MQ selectively inhibits NNMT (IC50 = 1.2 M), an enzyme that consumes nicotinamide by methylating it

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Their efficacy has not been confirmed by FDA-approved research, and they are not intended to diagnose, treat, cure, or prevent any disease

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[9] Because B vitamins are water-soluble, excess amounts are excreted in urine, which can lead to a noticeable change in urine color