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Interestingly, one of the studies showed that the use of antidepressants among depressed patients was protective of RA development [hazard ratio (HR) 0.74, 95% CI 0.710.76] (168), whereas another study found it to be associated with subsequent seronegative RA (HR 1.75, 95% CI 1.322.32) (169)

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The absence of long-term safety studies for most NPs, some of which have been fully developed for years, corroborates this dilemma

proposed FedSepsis, a federated deep-learning framework using electronic health records and IoMT devices for early sepsis detection, underscoring the potential of integrating predictive analytics with antioxidant-based therapeutics ( Conclusion The intricate interplay among oxidative stress, mitochondrial dysfunction, and immune dysregulation constitutes a central axis in the pathogenesis of sepsis

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