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The functional importance of intracellular communication mediated by EVs has been studied by several researchers

Integrating these approaches with conventional treatments such as phototherapy or topical corticosteroids may offer a comprehensive therapeutic strategy to manage vitiligo by protecting melanocytes from oxidative stress and ferroptosis (136)

This increases blood flow, possibly helping with RLS

Rectal gel application of Withania somnifera root extract expounds anti-inflammatory and muco-restorative activity in TNBS-induced inflammatory bowel disease

Journal for immunotherapy of cancer 11(8), 2023

For instance, the intracellular antioxidant defense systems (IADS) require the collaborative efforts of glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase (CAT), and others to uphold the cellular redox balance 45,46