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Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway

Although aging is associated with a fall in GSH content in both genders, male mice had more dramatic fall in GSH levels and GCL mRNA levels in many tissues (Wang et al., 2003)

Molecular graphics were generated using Pymol 62 and UCSF ChimeraX 63

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This hypothesis was confirmed in a recent study that the inflammation inhibitor IL-37 boosted MSU phagocytosis by macrophages, lowered the transcription of pyroptosis-associated proteins, and diminished the release of inflammatory cytokines post-phagocytosis, thereby mitigating the inflammatory response in gout (54)