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10.3389/fbioe.2021.736679 [DOI] [PMC free article] [PubMed] [Google Scholar] Bonthula S., Bonthula S

Spijker S, et al

doi: 10.1080/10408398.2020.1843398 7

Using our protocol we have also prepared the linaclotide drug for chronic constipation and irritable bowel syndrome, made of a 14 AAs peptide and bearing three disulfide bonds (Fig