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Funding This work was supported by grants obtained by IDI-IRCCS from the Italian Ministry of Health (Ricerca Corrente 2023 and 2024 and RF-2019-12368888 grant), LazioInnova (Grant A0375-2020-36568 UTV-IDI), European Union-NextGenerationEU through the Italian Ministry of University and research under PNRR-M4C2-I1.3 Project PE_00000019 HEAL ITALIA, and the European UnionNext Generation EUPNRR-MAD-202212375740 M6C2Investimento 2.1 Valorizzazione e potenziamento della ricerca biomedica del SSN, funded by the Italian Ministry of Health

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