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This detoxification can sometimes lead to temporary fatigue as the body expends energy to eliminate toxins

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[1] Glutathione reductaseEC 1.8.1.7C 4628 H 7378 O 1396 N 1272 S 52 P 4 [2] GSSG [3] [4] GSSGNADPHFAD [5] [5] [6] NADPHNADP + ^ [1] [] ^ Expasy - ProtParam

[23] On the other hand, certain drugs like isoniazid, hydralazine, and some penicillamine can cause vitamin B deficiency and might necessitate concurrent pyridoxine supplementation

You can also take it with or without food, but some studies suggest that taking it with a meal that contains carbohydrates and protein may increase its absorption

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