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Contrary to outdated recommendations that advised restricting protein due to concerns about Hepatic encephalopathy, multiple studies have shown that daily protein intake in the range of 1.21.5 g/kg does not increase the risk of hepatic encephalopathy and may, in fact, improve outcomes such as nitrogen balance, muscle preservation, and quality of life [5, 17,18,19,20]

Inconclusive : studies showing conflicting results or methodological limitations hindering evidence assessment

Pharmacogenetics of OPRM1

J Neurosci 21 : 44514459

This phenomenon might result in an increased presence of senescent cells, defined as cells that cease to divide but fail to die, thereby contributing to the aging of the cell population