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This distinguishes it from better-known compounds such as semaglutide (Ozempic/Wegovy), which targets only the GLP-1 receptor, and from tirzepatide (Mounjaro/Zepbound), which is a dual GLP-1/GIP agonist

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Reverse Mendelian randomization analysis In the main analysis, liability to NAFLD revealed positive association with vitamin B12, and the effect size of vitamin B12 concentrations in 1-SD change was 0.08 (95%CI, 0.01 to 0.16