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2023;8:345 Li X, Zhang HS

Significantly more potent and better tolerated than arsenic trioxide, Darinaparsin showed encouraging responses in T-cell lymphoma (Hosein et al., 2012) and AML (Nielsen et al., 2013) patients

89 It also induces a cytostatic effect on the cell cycle by deregulating extracellular signal-regulated protein kinases and subsequently suppressing cyclin E and cyclin-dependent kinase

(2018) 13(4):e0196405

Low levels of ROS act as second messengers for activating inflammatory intracellular signaling, such as NF-B and MAP kinase pathways (30)