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[1] [6] However, injectable therapy remains the first-line treatment in UK practice for pernicious anaemia and severe deficiency, as it bypasses absorption issues entirely

Some even claim B12 shots improve the appearance of their skin, hair and nails

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Organ meats are particularly rich sources

These include blood concentrations of total cobalamin, holo-transcobalamin (vitamin B 12 bound to transcobalamin, one of the two carrier proteins in blood

Both forms can effectively raise serum B12 levels and improve symptoms when taken at appropriate doses, though cyanocobalamin is more stable and cost-effective