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Manzanares D, Gonzalez C, Ivonnet P, Chen RS, Valencia-Gattas M, Conner GE, et al

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T., Jiang, Y

Increased copper has been linked to lipid peroxides

M-values, as a measure of melanin estimated using the Mexameter, were assessed after 4 and 8 weeks of therapy initiation

The translocation of phospholipids in cellular membranes, for example, PS exposure on the cell surface and cardiolipin translocation within the mitochondrial membranes, are key events in the initial phases of apoptosis and correlate with other major hallmarks of dying cells that include plasma membrane blebbing, cell shrinkage, loss of mitochondrial membrane potential, caspase activation, chromatin condensation, DNA fragmentation, and cytoskeleton remodeling