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Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies

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If a patient has been taking high-dose B12 in the weeks leading up to the blood test, the serum result may appear artificially reassuring while tissue stores remain low